Calculating the SNP-effective sample size from an alignment

Haubold, B.; Wiehe, T.

doi:10.1093/bioinformatics/18.1.36

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Calculating the SNP-effective sample size from an alignment

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Haubold, B.
Group of Genetics and Evolution, MPI for Chemical Ecology, Max Planck Society;

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Wiehe, T.
Group of Genetics and Evolution, MPI for Chemical Ecology, Max Planck Society;

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http://dx.doi.org/10.1093/bioinformatics/18.1.36
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Citation

Haubold, B., & Wiehe, T. (2002). Calculating the SNP-effective sample size from an alignment. Bioinformatics, 18(1), 36-38. doi:10.1093/bioinformatics/18.1.36.

Cite as: https://hdl.handle.net/11858/00-001M-0000-0012-B10C-4

Abstract

Motivation: The number of Single Nucleotide Polymorphisms (SNPs) detectable in an alignment is a function of the length and the number of the aligned sequences. The latter is called sample size. However, a typical alignment, for instance obtained as a B