Metabolism of imidacloprid and DDT by P450 CYP6G1 expressed in cell cultures of 
Nicotiana tabacum suggests detoxification of these insecticides in 
Cyp6g1-overexpressing strains of Drosophila melanogaster, leading to resistance

Joußen, Nicole; Heckel, D. G.; Haas, M.; Schuphan, I.; Schmidt, B.

doi:10.1002/ps.1472

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Metabolism of imidacloprid and DDT by P450 CYP6G1 expressed in cell cultures of Nicotiana tabacum suggests detoxification of these insecticides in Cyp6g1-overexpressing strains of Drosophila melanogaster, leading to resistance

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Heckel, D. G.
Department of Entomology, MPI for Chemical Ecology, Max Planck Society;

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Joußen, N., Heckel, D. G., Haas, M., Schuphan, I., & Schmidt, B. (2008). Metabolism of imidacloprid and DDT by P450 CYP6G1 expressed in cell cultures of Nicotiana tabacum suggests detoxification of these insecticides in Cyp6g1-overexpressing strains of Drosophila melanogaster, leading to resistance. Pest Management Science, 64(1), 65-73. doi:10.1002/ps.1472.

Cite as: https://hdl.handle.net/11858/00-001M-0000-0012-AA63-A

Abstract

BACKGROUND: With the worldwide use of insecticides, an increasing number of pest insect species have evolved target-site or metabolism-based resistance towards some of these compounds. The resulting decreased efficacy of pesticides threatens human welfa