Antitumor polyketide biosynthesis by an uncultivated bacterial symbiont of the 
marine sponge Theonella swinhoei

Piel, J.; Hui, D. Q.; Wen, G. P.; Butzke, D.; Platzer, M.; Fusetani, N.; Matsunaga, S.

doi:10.1073/pnas.0405976101

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Antitumor polyketide biosynthesis by an uncultivated bacterial symbiont of the marine sponge Theonella swinhoei

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Piel, J.
Department of Bioorganic Chemistry, MPI for Chemical Ecology, Max Planck Society;

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Hui, D. Q.
Department of Bioorganic Chemistry, MPI for Chemical Ecology, Max Planck Society;

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Butzke, D.
Department of Bioorganic Chemistry, MPI for Chemical Ecology, Max Planck Society;

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC528957/
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Citation

Piel, J., Hui, D. Q., Wen, G. P., Butzke, D., Platzer, M., Fusetani, N., et al. (2004). Antitumor polyketide biosynthesis by an uncultivated bacterial symbiont of the marine sponge Theonella swinhoei. Proceedings of the National Academy of Sciences of the United States of America, 101(46), 16222-16227. doi:10.1073/pnas.0405976101.

Cite as: https://hdl.handle.net/11858/00-001M-0000-0012-A28D-A

Abstract

Bacterial symbionts have long been suspected to be the true producers of many drug candidates isolated from marine invertebrates. Sponges, the most important marine source of biologically active natural products, have been frequently hypothesized to con