Spectrometrically monitored selection experiments: quantitative laser 
desorption mass spectrometry of small chemical libraries

Berlin, K.; Jain, R. K.; Tetzlaff, C.; Steinbeck, C.; Richert, C.

doi:10.1016/s1074-5521(97)90237-4

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Spectrometrically monitored selection experiments: quantitative laser desorption mass spectrometry of small chemical libraries

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Steinbeck, C.
Department of Bioorganic Chemistry, MPI for Chemical Ecology, Max Planck Society;

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引用

Berlin, K., Jain, R. K., Tetzlaff, C., Steinbeck, C., & Richert, C. (1997). Spectrometrically monitored selection experiments: quantitative laser desorption mass spectrometry of small chemical libraries. Chemistry & Biology, 4(1), 63-77. doi:10.1016/s1074-5521(97)90237-4.

引用: https://hdl.handle.net/11858/00-001M-0000-0012-9EA2-1

要旨

Background: Selection experiments involving chemical libraries are routinely used in the pharmaceutical industry for finding and optimizing lead compounds, In principle, almost any process involving a binding event or a reaction could be probed systemat