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Aureolic acids: Similar antibiotics with different biosynthetic gene clusters

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引用

O'Connor, S. E. (2004). Aureolic acids: Similar antibiotics with different biosynthetic gene clusters. Chemistry & Biology, 11(1), 8-10. doi:10.1016/j.chembiol.2004.01.006.


引用: https://hdl.handle.net/21.11116/0000-0002-A1ED-D
要旨
In this issue of Chemistry & Biology, Mendez and colleagues describe the sequence and organization of the chromomycin gene cluster [20]. Unexpectedly, the arrangement is starkly different from the mithramycin biosynthetic cluster, despite similarity in the individual genes and the near identical structures of the two antibiotic aureolic acids.