Substrate specificity of strictosidine synthase

McCoy, E; Galan, MC; O'Connor, Sarah E.

doi:10.1016/j.bmcl.2006.01.098

Item

ITEM ACTIONSEXPORT

Add to Basket

Local TagsRelease HistoryDetailsSummary

Released

Journal Article

Substrate specificity of strictosidine synthase

MPS-Authors

There are no MPG-Authors in the publication available

External Resource

No external resources are shared

Fulltext (restricted access)

There are currently no full texts shared for your IP range.

Fulltext (public)

There are no public fulltexts stored in PuRe

Supplementary Material (public)

There is no public supplementary material available

Citation

McCoy, E., Galan, M., & O'Connor, S. E. (2006). Substrate specificity of strictosidine synthase. Bioorganic & Medicinal Chemistry Letters, 16(9), 2475-2478. doi:10.1016/j.bmcl.2006.01.098.

Cite as: https://hdl.handle.net/21.11116/0000-0002-A1F8-0

Abstract

Strictosidine synthase catalyzes a Pictet-Spengler reaction in the first step in the biosynthesis of terpene indole alkaloids to generate strictosidine. The substrate requirements for strictosidine synthase are systematically and quantitatively examined and the enzymatically generated compounds are processed by the second enzyme in this biosynthetic pathway. (C) 2006 Elsevier Ltd. All rights reserved.