English
 
Help Privacy Policy Disclaimer
  Advanced SearchBrowse

Item

ITEM ACTIONSEXPORT

Released

Journal Article

Effect of bending anisotropy on the 3D conformation of short DNA loops

MPS-Authors
/persons/resource/persons219873

Golestanian,  R.
Department of Living Matter Physics, Max Planck Institute for Dynamics and Self-Organization, Max Planck Society;

External Resource
No external resources are shared
Fulltext (restricted access)
There are currently no full texts shared for your IP range.
Fulltext (public)
There are no public fulltexts stored in PuRe
Supplementary Material (public)
There is no public supplementary material available
Citation

Norouzi, D., Mohammad-Rafiee, F., & Golestanian, R. (2008). Effect of bending anisotropy on the 3D conformation of short DNA loops. Physical Review Letters, 101(16): 168103. doi:10.1103/PhysRevLett.101.168103.


Cite as: https://hdl.handle.net/21.11116/0000-0001-AD2F-9
Abstract
The equilibrium three dimensional shape of relatively short loops of DNA is studied using an elastic model that takes into account anisotropy in bending rigidities. Using a reasonable estimate for the anisotropy, it is found that cyclized DNA with lengths that are not integer multiples of the pitch take on nontrivial shapes that involve bending out of planes and formation of kinks. The effect of sequence inhomogeneity on the shape of DNA is addressed, and shown to enhance the geometrical features. These findings could shed some light on the role of DNA conformation in protein-DNA interactions. © 2008 The American Physical Society.