Elucidation of the downfield spectrum of human brain at 7T using multiple 
inversion recovery delays and echo times

Fichtner, ND; Henning, A; Zoelch, N; Boesch, C; Kreis, R

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Elucidation of the downfield spectrum of human brain at 7T using multiple inversion recovery delays and echo times

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Henning, A
Max Planck Institute for Biological Cybernetics, Max Planck Society;
Research Group MR Spectroscopy and Ultra-High Field Methodology, Max Planck Institute for Biological Cybernetics, Max Planck Society;
Department High-Field Magnetic Resonance, Max Planck Institute for Biological Cybernetics, Max Planck Society;

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Citation

Fichtner, N., Henning, A., Zoelch, N., Boesch, C., & Kreis, R. (2016). Elucidation of the downfield spectrum of human brain at 7T using multiple inversion recovery delays and echo times. Poster presented at 24th Annual Meeting and Exhibition of the International Society for Magnetic Resonance in Medicine (ISMRM 2016), Singapore.

Cite as: https://hdl.handle.net/21.11116/0000-0000-7B97-C

Abstract

Characterization of the full 1H spectrum may allow for better monitoring of pathologies and metabolism in humans. The downfield part (5-10ppm) is currently less well characterized than upfield; this work aims to benefit from higher field strength in order to quantify T1 and T2 in the downfield spectrum in human grey matter at 7T. We fitted downfield spectra to a heuristic model and obtained relaxation times for twelve peaks of interest. The T1’s are higher than those at 3T downfield; peaks with lower T1’s may include macromolecules. The T2’s are mostly shorter than those reported for upfield peaks at 7T.