Datensatz

Zusammenfassung

Questions concerning the self-organization of the genetic apparatus may be addressed within the framework of a model reactive polymer chemistry. The model divides reactions into specific biomolecular collisions leading to binding (recognition) and unimolecular relaxation (processing). The binding dynamics is integrated efficiently using a pattern matching collision table, and the processing is made potentially universal using a probabilistic and constructive variant of a Turing machine operating on a polymeric "tape". In this way a general unimolecular chemistry is complemented by the specific binding which characterizes biomolecular complex formation. The present model specifies a simple (stochastic) algorithm for the dependence of individual chemical reactions on macromolecular sequence and investigates the self-organization of reaction pathways showing sequence heredity, an emergent genetics.