A Sweet Deal for Diabetes

Villa, Mateo; Qiu, Jing; Pearce, Erika L.

doi:10.1016/j.tem.2017.10.006

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A Sweet Deal for Diabetes

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Villa, Mateo
Max Planck Institute of Immunobiology and Epigenetics, Max Planck Society;

Qiu, Jing
Max Planck Institute of Immunobiology and Epigenetics, Max Planck Society;

Pearce, Erika L.
Max Planck Institute of Immunobiology and Epigenetics, Max Planck Society;

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Citation

Villa, M., Qiu, J., & Pearce, E. L. (2018). A Sweet Deal for Diabetes. Trends in Endocrinology and Metabolism, 29, 1-2. doi:10.1016/j.tem.2017.10.006.

Cite as: https://hdl.handle.net/21.11116/0000-0000-BF66-7

Abstract

Sugars have pathogenic roles in diabetes. In Nature Medicine, Zhang et al. revisit this dogma and show that mannose induces the generation of regulatory T (Treg) cells. The immunoregulatory effect of mannose not only prevented the onset of autoimmune diabetes but also blocked disease progression in new-onset diabetic mice.