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Journal Article

Large-scale gradients in human cortical organization

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Huntenburg,  Julia M.
Max Planck Research Group Neuroanatomy and Connectivity, MPI for Human Cognitive and Brain Sciences, Max Planck Society;
Neurocomputation and Neuroimaging Unit, FU Berlin, Germany;

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Bazin,  Pierre-Louis
Social Brain Lab, The Netherlands Institute for Neuroscience, Royal Netherlands Academy of Arts and Sciences, Amsterdam, the Netherlands;
Spinoza Centre for Neuroimaging, University of Amsterdam, the Netherlands;
Department Neurophysics (Weiskopf), MPI for Human Cognitive and Brain Sciences, Max Planck Society;

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Margulies,  Daniel S.
Max Planck Research Group Neuroanatomy and Connectivity, MPI for Human Cognitive and Brain Sciences, Max Planck Society;

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Huntenburg_Bazin_2017.pdf
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Citation

Huntenburg, J. M., Bazin, P.-L., & Margulies, D. S. (2018). Large-scale gradients in human cortical organization. Trends in Cognitive Sciences, 22(1), 21-31. doi:10.1016/j.tics.2017.11.002.


Cite as: https://hdl.handle.net/11858/00-001M-0000-002E-88F2-D
Abstract
Recent advances in mapping cortical areas in the human brain provide a basis for investigating the significance of their spatial arrangement. Here we describe a dominant gradient in cortical features that spans between sensorimotor and transmodal areas. We propose that this gradient constitutes a core organizing axis of the human cerebral cortex, and describe an intrinsic coordinate system on its basis. Studying the cortex with respect to these intrinsic dimensions can inform our understanding of how the spectrum of cortical function emerges from structural constraints.