English
 
Help Privacy Policy Disclaimer
  Advanced SearchBrowse

Item

ITEM ACTIONSEXPORT

Released

Journal Article

Miniature random-access fiber scanner for in vivo multiphoton imaging

MPS-Authors
/persons/resource/persons95132

Sawinski,  Jürgen
Department of Biomedical Optics, Max Planck Institute for Medical Research, Max Planck Society;

/persons/resource/persons128986

Denk,  Winfried
Department of Biomedical Optics, Max Planck Institute for Medical Research, Max Planck Society;

Fulltext (restricted access)
There are currently no full texts shared for your IP range.
Fulltext (public)
There are no public fulltexts stored in PuRe
Supplementary Material (public)
There is no public supplementary material available
Citation

Sawinski, J., & Denk, W. (2007). Miniature random-access fiber scanner for in vivo multiphoton imaging. Journal of Applied Physics, 102(3): 034701, pp. 1-8. doi:10.1063/1.2763945.


Cite as: https://hdl.handle.net/11858/00-001M-0000-002C-AD4A-2
Abstract
Multiphoton microscopy allows imaging of cellular activity in living tissue explants and in whole animals and has thus become a powerful tool for studying neuronal activity. The miniaturization of laser-scanning microscopy promises to extend activity measurements to awake, freely moving animals. Here we describe and evaluate a miniature multiphoton microscope based on a “piezolever fiber scanner” (PLFS). Our current PLFS has a scan range of 1.1 mm and a resonance frequency of 790 Hz. It allows, unlike resonance-based designs, a lateral shift of the scanned area, and offers the prospect of random-access (vector) scanning.