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Expanding the genetic code for site-specific labelling of tobacco mosaic virus coat protein and building biotin-functionalized virus-like particles

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Wu,  F. C.
Vollmer Research Group, Research Groups, Max Planck Institute for the Science of Light, Max Planck Society;

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Ballard,  Z.
Vollmer Research Group, Research Groups, Max Planck Institute for the Science of Light, Max Planck Society;

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Citation

Wu, F. C., Zhang, H., Zhou, Q., Wu, M., Ballard, Z., Tian, Y., et al. (2014). Expanding the genetic code for site-specific labelling of tobacco mosaic virus coat protein and building biotin-functionalized virus-like particles. CHEMICAL COMMUNICATIONS, 50(30), 4007-4009. doi:10.1039/c3cc49137d.


Cite as: https://hdl.handle.net/11858/00-001M-0000-002D-668B-E
Abstract
A method for site-specific and high yield modification of tobacco mosaic virus coat protein (TMVCP) utilizing a genetic code expanding technology and copper free cycloaddition reaction has been established, and biotin-functionalized virus-like particles were built by the self-assembly of the protein monomers.