Vaccine against carbapenem-resistant klebsiella pneumoniae

Seeberger, Peter H.; Pereira, Claney Lebev; Xiao, Guozhi; Khan, Naeem; Chakkumkal, Anish

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特許

Vaccine against carbapenem-resistant klebsiella pneumoniae

MPS-Authors

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Seeberger, Peter H.
Peter H. Seeberger, Biomolekulare Systeme, Max Planck Institute of Colloids and Interfaces, Max Planck Society;

/persons/resource/persons121719

Pereira, Claney Lebev
Peter H. Seeberger - Vaccine Development, Biomolekulare Systeme, Max Planck Institute of Colloids and Interfaces, Max Planck Society;

/persons/resource/persons181530

Xiao, Guozhi
Biomolekulare Systeme, Max Planck Institute of Colloids and Interfaces, Max Planck Society;

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Khan, Naeem
Biomolekulare Systeme, Max Planck Institute of Colloids and Interfaces, Max Planck Society;

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Chakkumkal, Anish
Chakkumal Anish, Biomolekulare Systeme, Max Planck Institute of Colloids and Interfaces, Max Planck Society;

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2364355.pdf
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引用

Vaccine against carbapenem-resistant klebsiella pneumoniae.(2016).

引用: https://hdl.handle.net/11858/00-001M-0000-002C-038D-9

要旨

The present invention relates to synthetic saccharides of general fornnula (I): V*−[Ux+2−Ux+ 1−Ux]n−V−O−L−NH2 that are related to carbapenem-resistant Kliebsella pneumoniae capsular polysaccharide and conjugates thereof. Said conjugates and pharmaceutical composition containing said conjugates are useful for prevention and/or treatment of diseases associated with carbapenem-resistant Klebsiella pneumoniae. Furthermore, the synthetic saccharides of general formula (I): V*−[Ux+2−Ux+1−Ux]n−V−O−L−NH2 are useful as marker in immunological assays for detection of antibodies against carbapenem-resistant Klebsiella pneumoniae bacteria.