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How Does the Molecular Machine That Drives Energy Conversion in the Cell Membrane Work?

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Kühlbrandt,  Werner
Department of Structural Biology, Max Planck Institute of Biophysics, Max Planck Society;

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Citation

Kühlbrandt, W. (2016). How Does the Molecular Machine That Drives Energy Conversion in the Cell Membrane Work? doi:10.21036/LTPUB10234.


Cite as: https://hdl.handle.net/11858/00-001M-0000-002B-BBC7-8
Abstract
Cells need to convert the energy derived from food to perform functions like muscle contractions. A “molecular machine” in the cell membrane plays a key role in this process. It works like a rotor and converts one component into another. In this video WERNER KÜHLBRANDT describes how the scientists used state-of-the-art electron microscopy to study the structure of this nanometer turbine down to the atomic level. The obtained data was then used to create a 3D model of the molecule. The surprising finding is the orientation of the rotor elements that goes against established knowledge of membrane molecule structure.