English
 
Help Privacy Policy Disclaimer
  Advanced SearchBrowse

Item

ITEM ACTIONSEXPORT
Add to Basket
  Local TagsRelease HistoryDetailsSummary

Released
Journal Article

Exploring substrate scope and stereoselectivity of P450 peroxygenase OleTJE in olefin-forming oxidative decarboxylation

MPS-Authors
/persons/resource/persons187647

Wang,  Jianbo
Research Department Reetz, Max-Planck-Institut für Kohlenforschung, Max Planck Society;

/persons/resource/persons137066

Lonsdale,  Richard
Research Department Reetz, Max-Planck-Institut für Kohlenforschung, Max Planck Society;

External Resource

http://pubs.rsc.org/en/Content/ArticleLanding/2016/CC/C6CC04345C#!divAbstract
(Abstract)

Fulltext (restricted access)
There are currently no full texts shared for your IP range.
Fulltext (public)
There are no public fulltexts stored in PuRe
Supplementary Material (public)
There is no public supplementary material available
Citation

Wang, J., Lonsdale, R., & Reetz, M. T. (2016). Exploring substrate scope and stereoselectivity of P450 peroxygenase OleTJE in olefin-forming oxidative decarboxylation. Chemical Communications, 52, 8131-8133. doi:10.1039/C6CC04345C.


Cite as: https://hdl.handle.net/11858/00-001M-0000-002B-2E8F-F
Abstract
As recently reported, the olefin-forming oxidative decarboxylation of straight-chain C4–C22 carboxylic acids catalyzed by P450 peroxygenase OleTJE constitutes a mild alkene synthesis. The present study shows that structurally different carboxylic acids are also accepted, including those that generate di-substituted olefins. Exploratory mutational experiments lead to increased trans-selectivity.