Can Biosignatures Be Used to Develop a Reliable, Fast and Low-Cost Test for 
Tuberculosis?

Kaufmann, Stephan H.E.

doi:dx.doi.org/10.21036/LTPUB10210

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Can Biosignatures Be Used to Develop a Reliable, Fast and Low-Cost Test for Tuberculosis?

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Kaufmann, Stephan H.E.
Department of Immunology, Max Planck Institute for Infection Biology, Max Planck Society;

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https://lt.org/publication/can-biosignatures-be-used-develop-reliable-fast-and-low-cost-test-tuberculosis
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Citation

Kaufmann, S. H. (2016). Can Biosignatures Be Used to Develop a Reliable, Fast and Low-Cost Test for Tuberculosis? doi:dx.doi.org/10.21036/LTPUB10210.

Cite as: https://hdl.handle.net/11858/00-001M-0000-002B-BB93-D

Abstract

Tuberculosis is still a major health issue and the number one killer of all contagious diseases. But while more than 2 billion people are infected with the tuberculosis agent, only 10% develop an active disease. Current diagnostic tests cannot distinguish between infected people and people with active tuberculosis. In this video, STEFAN H. E. KAUFMANN explains that they found a characteristic gene expression profile of people infected with tuberculosis. Relying on only four markers they developed a highly sensitive method that is not only able to identify people with active tuberculosis but is also suitable for point of care application in countries with low resources.