Synthesis of Oxindoles by Brønsted Acid Catalyzed Radical Cascade Addition of 
Ketones

Boess, Esther; Karanestora, Sofia; Bosnidou, Alexandra-Eleni; Schweitzer-Chaput, Bertrand; Hasenbeck, Max; Klussmann, Martin

doi:10.1055/s-0034-1381052

アイテム詳細

登録内容を編集ファイル形式で保存

一時保存へ追加

タグ情報を表示リリース履歴を表示詳細要約

公開

学術論文

Synthesis of Oxindoles by Brønsted Acid Catalyzed Radical Cascade Addition of Ketones

MPS-Authors

/persons/resource/persons58448

Boess, Esther
Research Group Klußmann, Max-Planck-Institut für Kohlenforschung, Max Planck Society;

/persons/resource/persons58987

Schweitzer-Chaput, Bertrand
Research Group Klußmann, Max-Planck-Institut für Kohlenforschung, Max Planck Society;

/persons/resource/persons58702

Klussmann, Martin
Research Group Klußmann, Max-Planck-Institut für Kohlenforschung, Max Planck Society;
Research Group Klußmann, Max-Planck-Institut für Kohlenforschung, Max Planck Society;

External Resource

There are no locators available

Fulltext (restricted access)

There are currently no full texts shared for your IP range.

フルテキスト (公開)

公開されているフルテキストはありません

付随資料 (公開)

There is no public supplementary material available

引用

Boess, E., Karanestora, S., Bosnidou, A.-E., Schweitzer-Chaput, B., Hasenbeck, M., & Klussmann, M. (2015). Synthesis of Oxindoles by Brønsted Acid Catalyzed Radical Cascade Addition of Ketones. Synlett, 26(14), 1973-1976. doi:10.1055/s-0034-1381052.

引用: https://hdl.handle.net/11858/00-001M-0000-0029-2E66-7

要旨

Oxindoles bearing ketone side chains in the 3-position can be synthesized by BrOnsted acid catalysis from N-aryl methacrylamides, ketones, and hydroperoxides. The cyclized products are presumably formed in a radical cascade reaction, initiated by decay of intermediate alkenyl peroxides. In the case of acrylic substrates that do not undergo cyclization, -peroxyketones were isolated instead, indicating that the final cyclization step of the cascade does not take place in these cases.