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Journal Article

The discovery of de novo gene evolution

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Tautz,  Diethard
Department Evolutionary Genetics, Max Planck Institute for Evolutionary Biology, Max Planck Society;

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http://muse.jhu.edu/article/556931
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Citation

Tautz, D. (2014). The discovery of de novo gene evolution. Perspectives in Biology and Medicine, 57(1), 149-161. doi:10.1353/pbm.2014.0006.


Cite as: https://hdl.handle.net/11858/00-001M-0000-0024-3416-1
Abstract
Genes can evolve via duplication and divergence mechanisms, but also de novo out of non-coding intergenic sequences. This latter mechanism has only recently become fully appreciated, while the former mechanism was an almost exclusive dogma for quite some time. This essay explores the history of this development: why a view developed, with the alternative hardly being explored. Because of the prevailing view, an important aspect of the nature of genes and their evolutionary origin escaped our attention. Evidence is now rapidly accumulating that de novo evolution is a very active mechanism for generating novelty in the