Quantal neurotransmitter release from early endosomes?

Bauerfeind , Rudolf; Huttner , Wieland B.; Almers, Wolfhard; Augustine , George J.

doi:10.1016/0962-8924(94)90191-0

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Quantal neurotransmitter release from early endosomes?

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Almers, Wolfhard
Department of Molecular Cell Research, Max Planck Institute for Medical Research, Max Planck Society;

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http://dx.doi.org/10.1016/0962-8924(94)90191-0
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Bauerfeind, R., Huttner, W. B., Almers, W., & Augustine, G. J. (1994). Quantal neurotransmitter release from early endosomes? Trends in Cell Biology, 4(5), 155-156. doi:10.1016/0962-8924(94)90191-0.

Cite as: https://hdl.handle.net/11858/00-001M-0000-0019-A91D-4

Abstract

Neurotransmitters are stored in, and released from, synaptic vesicles. The release of neurotransmitter, which typically occurs in response to an action potential in a Ca2+-dependent manner, causes the postsynaptic potential. When neurotransmitter is released from only a single or a few synaptic vesicles, the postsynaptic potential is clearly seen to be quantaI'. The uniform amplitude of the quanta presumably reflects the uniform volume and neurotransmitter content of synaptic vesicles