GeneCAT - novel webtools that combine BLAST and co-expression analyses

Mutwil, M.; Obro, J.; Willats, W. G. T.; Persson, S.

doi:10.1093/Nar/Gkn292

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GeneCAT - novel webtools that combine BLAST and co-expression analyses

MPG-Autoren

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Mutwil, M.
Plant Cell Walls - Persson, Max Planck Research Groups, Max Planck Institute of Molecular Plant Physiology, Max Planck Society;
Regulatory Networks, Department Stitt, Max Planck Institute of Molecular Plant Physiology, Max Planck Society;

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Persson, S.
Plant Cell Walls - Persson, Max Planck Research Groups, Max Planck Institute of Molecular Plant Physiology, Max Planck Society;

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Mutwil, M., Obro, J., Willats, W. G. T., & Persson, S. (2008). GeneCAT - novel webtools that combine BLAST and co-expression analyses. Nucleic Acids Research, 36(Web Server issue), W320-W326. doi:10.1093/Nar/Gkn292.

Zitierlink: https://hdl.handle.net/11858/00-001M-0000-0014-26F5-A

Zusammenfassung

The gene co-expression analysis toolbox (GeneCAT) introduces several novel microarray data analyzing tools. First, the multigene co-expression analysis, combined with co-expressed gene networks, provides a more powerful data mining technique than standard, single-gene co-expression analysis. Second, the high-throughput Map-O-Matic tool matches co-expression pattern of multiple query genes to genes present in user-defined subdatabases, and can therefore be used for gene mapping in forward genetic screens. Third, Rosetta combines co-expression analysis with BLAST and can be used to find true gene orthologs in the plant model organisms Arabidopsis thaliana and Hordeum vulgare (Barley). GeneCAT is equipped with expression data for the model plant A. thaliana, and first to introduce co-expression mining tools for the monocot Barley. GeneCAT is available at http://genecat.mpg.de.