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Co-occurrence of phenylphenalenones and flavonoids in Xiphidium caeruleum Aubl. flowers

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Fang,  Jingjing
Research Group Biosynthesis / NMR, MPI for Chemical Ecology, Max Planck Society;
IMPRS on Ecological Interactions, MPI for Chemical Ecology, Max Planck Society;

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Hölscher,  Dirk
Research Group Biosynthesis / NMR, MPI for Chemical Ecology, Max Planck Society;

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Schneider,  Bernd
Research Group Biosynthesis / NMR, MPI for Chemical Ecology, Max Planck Society;

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Citation

Fang, J., Hölscher, D., & Schneider, B. (2012). Co-occurrence of phenylphenalenones and flavonoids in Xiphidium caeruleum Aubl. flowers. Phytochemistry, 82, 143-148. doi:10.1016/j.phytochem.2012.07.005.


Cite as: https://hdl.handle.net/11858/00-001M-0000-000F-AAF9-8
Abstract
Insecticidal crystal toxins from the bacterium Bacillus thuringiensis (Bt) kill insects via a complex mode of action resulting in the creation of cytolytic pores in the membrane of midgut epithelial cells. Recent genetic studies in four species of Lepidoptera have found mutations in an ABC transporter in strains that have evolved resistance to Cry1A toxins. This points to a novel role of ABC proteins in insertion of pores into the membrane, and suggests strategies to increase efficacy of and delay resistance to Bt toxins.