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Antitumor polyketide biosynthesis by an uncultivated bacterial symbiont of the marine sponge Theonella swinhoei

MPS-Authors
http://pubman.mpdl.mpg.de/cone/persons/resource/persons4095

Piel,  J.
Department of Bioorganic Chemistry, MPI for Chemical Ecology, Max Planck Society;

http://pubman.mpdl.mpg.de/cone/persons/resource/persons3940

Hui,  D. Q.
Department of Bioorganic Chemistry, MPI for Chemical Ecology, Max Planck Society;

http://pubman.mpdl.mpg.de/cone/persons/resource/persons3826

Butzke,  D.
Department of Bioorganic Chemistry, MPI for Chemical Ecology, Max Planck Society;

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Citation

Piel, J., Hui, D. Q., Wen, G. P., Butzke, D., Platzer, M., Fusetani, N., et al. (2004). Antitumor polyketide biosynthesis by an uncultivated bacterial symbiont of the marine sponge Theonella swinhoei. Proceedings of the National Academy of Sciences of the United States of America, 101(46), 16222-16227.


Cite as: http://hdl.handle.net/11858/00-001M-0000-0012-A28D-A
Abstract
Bacterial symbionts have long been suspected to be the true producers of many drug candidates isolated from marine invertebrates. Sponges, the most important marine source of biologically active natural products, have been frequently hypothesized to con