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Journal Article

Sequence and expression of human GABAA receptor α1 and β1 subunits

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Citation

Schofield, P. R., Pritchett, D. B., Sontheimer, H., Kettenmann, H., & Seeburg, P. H. (1989). Sequence and expression of human GABAA receptor α1 and β1 subunits. FEBS Letters, 244(2), 361-364. doi:10.1016/0014-5793(89)80563-0.

Abstract

The deduced amino acid sequences of cDNA clones encoding human GABAA receptor alpha 1 and beta 1 subunits are presented. The human subunits display very high levels of sequence identity with the corresponding bovine receptor subunits. The cloned human GABAA receptor subunits induce the formation of GABA−gated chloride channels when expressed in mammalian cells