Backwards and Forwards Binding

Saraste, Matti; Musacchio, Andrea

doi:10.1038/nsb1294-835

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Backwards and Forwards Binding

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Musacchio, Andrea
Abt. I:Mechanistische Zellbiologie, Max Planck Institute of Molecular Physiology, Max Planck Society;

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Citation

Saraste, M., & Musacchio, A. (1994). Backwards and Forwards Binding. NATURE STRUCTURAL BIOLOGY, 1(12), 835-837. doi:10.1038/nsb1294-835.

Cite as: https://hdl.handle.net/11858/00-001M-0000-0015-3B2D-3

Abstract

New structures of SH3 domains complexed with proline-rich peptides show that the ligands can bind in two opposite orientations; this feature has not been seen before in protein/protein recognition.