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Journal Article

Biosynthesis with Fluorine

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http://pubman.mpdl.mpg.de/cone/persons/resource/persons101503

Sánchez-García,  Elsa
Research Group Sánchez-García, Max-Planck-Institut für Kohlenforschung, Max Planck Society;

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Citation

Klopries, S., Koopmans, K. R. M., Sánchez-García, E., & Schulz, F. (2014). Biosynthesis with Fluorine. ChemBioChem: A European Journal of Chemical Biology, 15(4), 495-497. doi:10.1002/cbic.201300750.


Cite as: http://hdl.handle.net/11858/00-001M-0000-0018-B24A-A
Abstract
No longer in-F-able: Fluorine building blocks can be used in polyketide biosynthesis. This represents a more flexible approach to organofluorines than the traditional use of fluorinated starter units in multistep organic syntheses, and will hopefully increase the number of compounds available for drug development.