Second-Generation Total Synthesis of Spirastrellolide F Methyl Ester: The 
Alkyne Route

Benson, Stefan; Collin, Marie-Pierre; Arlt, Alexander; Gabor, Barbara; Goddard, Richard; Fürstner, Alois

doi:10.1002/anie.201103270

Item

ITEM ACTIONSEXPORT

Add to Basket

Local TagsRelease HistoryDetailsSummary

Released

Journal Article

Second-Generation Total Synthesis of Spirastrellolide F Methyl Ester: The Alkyne Route

MPS-Authors

/persons/resource/persons58425

Benson, Stefan
Research Department Fürstner, Max-Planck-Institut für Kohlenforschung, Max Planck Society;

/persons/resource/persons58492

Collin, Marie-Pierre
Research Department Fürstner, Max-Planck-Institut für Kohlenforschung, Max Planck Society;

/persons/resource/persons58400

Arlt, Alexander
Research Department Fürstner, Max-Planck-Institut für Kohlenforschung, Max Planck Society;

/persons/resource/persons58558

Gabor, Barbara
Service Department Farès (NMR), Max-Planck-Institut für Kohlenforschung, Max Planck Society;

/persons/resource/persons58578

Goddard, Richard
Service Department Lehmann (EMR), Max-Planck-Institut für Kohlenforschung, Max Planck Society;

/persons/resource/persons58380

Fürstner, Alois
Research Department Fürstner, Max-Planck-Institut für Kohlenforschung, Max Planck Society;

External Resource

No external resources are shared

Fulltext (restricted access)

There are currently no full texts shared for your IP range.

Fulltext (public)

There are no public fulltexts stored in PuRe

Supplementary Material (public)

anie_201103270_sm_miscellaneous_information.pdf
(Supplementary material), 3MB

Citation

Benson, S., Collin, M.-P., Arlt, A., Gabor, B., Goddard, R., & Fürstner, A. (2011). Second-Generation Total Synthesis of Spirastrellolide F Methyl Ester: The Alkyne Route. Angewandte Chemie International Edition, 50(37), 8739-8744. doi:10.1002/anie.201103270.

Cite as: https://hdl.handle.net/11858/00-001M-0000-0014-CA40-1

Abstract

Outlandish: The spiroketal embedded in spirastrellolide F methyl ester is a daring site for ring closure, yet it has allowed the power of catalytic alkyne scission and activation to be showcased. An improved strategy for the introduction of the labile side chain was also developed.