de.mpg.escidoc.pubman.appbase.FacesBean
English
 
Help Guide Disclaimer Contact us Login
  Advanced SearchBrowse

Item

ITEM ACTIONSEXPORT

Released

Journal Article

A Versatile Lab to Pilot Scale Continuous Reaction System for Supercritical Fluid Processing

MPS-Authors
http://pubman.mpdl.mpg.de/cone/persons/resource/persons58749

Leitner,  Walter
Institut für Technische und Makromolekulare Chemie, RWTH Aachen University;
Service Department Leitner (Technical Labs), Max-Planck-Institut für Kohlenforschung, Max Planck Society;

Locator
There are no locators available
Fulltext (public)
There are no public fulltexts available
Supplementary Material (public)
There is no public supplementary material available
Citation

Hintermair, U., Roosen, C., Kaever, M., Kronenberg, H., Thelen, R., Aey, S., et al. (2011). A Versatile Lab to Pilot Scale Continuous Reaction System for Supercritical Fluid Processing. Organic Process Research & Development, 15(6), 1275-1280. doi:10.1021/op200053w.


Cite as: http://hdl.handle.net/11858/00-001M-0000-0014-A316-0
Abstract
A compact and versatile continuous reaction system for supercritical fluids as mobile phase was realised using commercially available components where possible. All process parameters of particular importance to the specific properties of near- or supercritical fluids such as pressure, temperature, and composition (p, T, x) can be accurately controlled over a wide flow range. The setup is completely automated by the help of computerised control and features a view cell for inline phase behavior observation. Coupling to supercritical fluid chromatography permits sampling under process conditions for reaction monitoring. Potential applications include continuous flow synthesis and catalysis, extractions, and other operations demanding controlled application of compressible gases. Highly efficient continuous flow asymmetric hydrogenation catalysis with integrated product separation is demonstrated.