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Journal Article

Catalytic Acylcyanation of Imines with Acetylcyanide

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Pan,  Subhas Chandra
Research Department List, Max-Planck-Institut für Kohlenforschung, Max Planck Society;

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Zhou,  Jian
Research Department Schüth, Max-Planck-Institut für Kohlenforschung, Max Planck Society;

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List,  Benjamin
Research Department List, Max-Planck-Institut für Kohlenforschung, Max Planck Society;

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Citation

Pan, S. C., Zhou, J., & List, B. (2006). Catalytic Acylcyanation of Imines with Acetylcyanide. Synlett, (19), 3275-3276. doi:10.1055/s-2006-951543.


Cite as: https://hdl.handle.net/11858/00-001M-0000-0014-A45E-8
Abstract
Aldimines react with acetyl cyanide in the presence of a catalytic amount of a thiourea catalyst to give the corresponding N-acetylated amino nitriles in high yields. The scope of the reaction is broad and both aromatic as well as aliphatic aldimines can readily be used.