‘High-Surface Sodium' as a Reducing Agent for TiCl3

Fürstner, Alois; Seidel, Günter

doi:10.1055/s-1995-3854

Item

ITEM ACTIONSEXPORT

Add to Basket

Local TagsRelease HistoryDetailsSummary

Released

Journal Article

‘High-Surface Sodium' as a Reducing Agent for TiCl₃

MPS-Authors

/persons/resource/persons58380

Fürstner, Alois
Research Department Fürstner, Max-Planck-Institut für Kohlenforschung, Max Planck Society;

/persons/resource/persons58992

Seidel, Günter
Research Department Fürstner, Max-Planck-Institut für Kohlenforschung, Max Planck Society;

External Resource

No external resources are shared

Fulltext (restricted access)

There are currently no full texts shared for your IP range.

Fulltext (public)

There are no public fulltexts stored in PuRe

Supplementary Material (public)

There is no public supplementary material available

Citation

Fürstner, A., & Seidel, G. (1995). ‘High-Surface Sodium' as a Reducing Agent for TiCl₃. Synthesis, (1), 63-68. doi:10.1055/s-1995-3854.

Cite as: https://hdl.handle.net/11858/00-001M-0000-0014-A487-8

Abstract

Sodium deposited on inorganic supports such as Al₂O₃, TiO₂ and NaCl (‘high-surface sodium') is a cheap, readily prepared, nonpyrophoric reducing agent for TiCl₃. The low-valent titanium thus obtained, after only 1 h reduction time, is well suited for McMurry coupling reactions, particularly of aromatic carbonyl compounds. It exhibits a previously unrivalled template effect for the cyclization of dicarbonyl compounds to (macrocyclic) cycloalkenes and is suitable for the reduction of N-acyl-2-aminobenzophenone derivatives to 2,3-disubstituted indoles. Even a 36-membered ring could be formed without recourse to high dilution techniques.