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Modeling RNA loops using sequence homology and geometric constraints

MPS-Authors
http://pubman.mpdl.mpg.de/cone/persons/resource/persons97397

Schudoma,  C.
BioinformaticsCIG, Infrastructure Groups and Service Units, Max Planck Institute of Molecular Plant Physiology, Max Planck Society;

http://pubman.mpdl.mpg.de/cone/persons/resource/persons97298

May,  P.
BioinformaticsCIG, Infrastructure Groups and Service Units, Max Planck Institute of Molecular Plant Physiology, Max Planck Society;

http://pubman.mpdl.mpg.de/cone/persons/resource/persons97467

Walther,  D.
BioinformaticsCIG, Infrastructure Groups and Service Units, Max Planck Institute of Molecular Plant Physiology, Max Planck Society;

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Schudoma, C., May, P., & Walther, D. (2010). Modeling RNA loops using sequence homology and geometric constraints. Bioinformatics, 26(13), 1671-1672. doi:10.1093/bioinformatics/btq236.


Cite as: http://hdl.handle.net/11858/00-001M-0000-0014-2339-A
Abstract
RNA loop regions are essential structural elements of RNA molecules influencing both their structural and functional properties. We developed RLooM, a web application for homology-based modeling of RNA loops utilizing template structures extracted from the PDB. RLooM allows the insertion and replacement of loop structures of a desired sequence into an existing RNA structure. Furthermore, a comprehensive database of loops in RNA structures can be accessed through the web interface.