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Poster

Reproducibility of the BOLD response in the human brain as measured at high-resolution at 7 Tesla

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Shmuel, A
Department Physiology of Cognitive Processes, Max Planck Institute for Biological Cybernetics, Max Planck Society;

/persons/resource/persons84137

Yacoub E, Pfeuffer, J
Department Physiology of Cognitive Processes, Max Planck Institute for Biological Cybernetics, Max Planck Society;

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Citation

Shmuel, A., Yacoub E, Pfeuffer, J., Moortele P-FVD, Adriany G, Ugurbil, K., & Hu, X. (2001). Reproducibility of the BOLD response in the human brain as measured at high-resolution at 7 Tesla. Poster presented at 9th Scientific Meeting of the International Society of Magnetic Resonance in Medicine (ISMRM), 18th Annual Meeting and Exhibition of the European Society for Magnetic Resonance in Medicine and Biology (ESMRMB), Glasgow, UK.

Abstract

Theoretical considerations as well as experimental studies have suggested that imaging at high fields is advantageous for fMRI. Specifically: 1) the signal to noise ratio (SNR) of the images is expected to increase; 2) the contrast to noise ratio (CNR) of the BOLD response is expected to increase; and 3) the specificity of BOLD response to the gray matter is expected to improve. The anticipated increase in SNR and CNR, and the decrease in signal from the blood vessels are supposed to bring about a high degree of reproducibility of the BOLD response at high field. In this study we have investigated the reproducibility of the BOLD response obtained from the human brain at high-resolution at 7 Tesla.