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Functional MR imaging of the monkey brain in a novel vertical large-bore 7 Tesla setup

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http://pubman.mpdl.mpg.de/cone/persons/resource/persons84137

Pfeuffer,  J
Department Physiology of Cognitive Processes, Max Planck Institute for Biological Cybernetics, Max Planck Society;

http://pubman.mpdl.mpg.de/cone/persons/resource/persons84805

Merkle,  H
Max Planck Institute for Biological Cybernetics, Max Planck Society;

http://pubman.mpdl.mpg.de/cone/persons/resource/persons84063

Logothetis,  NK
Department Physiology of Cognitive Processes, Max Planck Institute for Biological Cybernetics, Max Planck Society;

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Citation

Pfeuffer, J., Merkle, H., & Logothetis, N. (2002). Functional MR imaging of the monkey brain in a novel vertical large-bore 7 Tesla setup. Poster presented at 19th Annual Scientific Meeting of the ESMRMB 2002, Cannes, France.


Cite as: http://hdl.handle.net/11858/00-001M-0000-0013-DF56-0
Abstract
Functional MRI in monkeys promises to build a bridge between brain research in humans and the large body of systems neuroscience work in animals [1]. Simultaneous fMRI and electrophysiology was recently used in the anesthetized monkey to elucidate the neural activity underlying the fMRI BOLD signal [2]. Here we present the first results from a novel high field (7T), large-bore (60cm) vertical MR system, in which MR imaging and electrophysiology can be performed in the awake trained monkey (Macaca mulatta). Upright positioning of the animal - being used over the last 50-years in all alert-monkey laboratories, was chosen for fMRI too, to minimize discomfort in the animals, expedite their training process, and ensure longer cooperation during the demanding psychophysical testing.