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Perfusion-based high-resolution fMRI in the primate brain using a novel vertical large-bore 7 Tesla setup

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http://pubman.mpdl.mpg.de/cone/persons/resource/persons84137

Pfeuffer,  J
Department Physiology of Cognitive Processes, Max Planck Institute for Biological Cybernetics, Max Planck Society;

http://pubman.mpdl.mpg.de/cone/persons/resource/persons84805

Merkle,  H
Max Planck Institute for Biological Cybernetics, Max Planck Society;

http://pubman.mpdl.mpg.de/cone/persons/resource/persons84063

Logothetis,  NK
Department Physiology of Cognitive Processes, Max Planck Institute for Biological Cybernetics, Max Planck Society;

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Citation

Pfeuffer, J., Merkle, H., & Logothetis, N. (2005). Perfusion-based high-resolution fMRI in the primate brain using a novel vertical large-bore 7 Tesla setup. Poster presented at 13th Scientific Meeting of the International Society of Magnetic Resonance in Medicine (ISMRM 2005), Miami Beach, FL, USA.


Cite as: http://hdl.handle.net/11858/00-001M-0000-0013-D5AB-D
Abstract
The first high-resolution CBF maps in the Macaca mulatta are shown that were obtained with 500 μm in-plane resolution (single-shot GE-FAIR). High sensitivity was achieved by using a 7 T system and custom-made RF coils in TORO mode. Functional changes of CBF was found to be robust in the macaque primary visual cortex (38 / 21 changes during activation). The functional CBF change was entirely localized within gray matter cortex, providing unequivocal evidence for its high spatial specificity. Functional contrast-to-noise ratio was mainly determined by capillary contributions and was independent of baseline CBF.