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Poster

Continuous arterial spin labeling (CASL) in the monkey brain at high magnetic field using a three-coil approach

MPG-Autoren
http://pubman.mpdl.mpg.de/cone/persons/resource/persons84326

Zappe,  AC
Department Physiology of Cognitive Processes, Max Planck Institute for Biological Cybernetics, Max Planck Society;

http://pubman.mpdl.mpg.de/cone/persons/resource/persons84805

Merkle,  H
Max Planck Institute for Biological Cybernetics, Max Planck Society;

http://pubman.mpdl.mpg.de/cone/persons/resource/persons84063

Logothetis,  NK
Department Physiology of Cognitive Processes, Max Planck Institute for Biological Cybernetics, Max Planck Society;

http://pubman.mpdl.mpg.de/cone/persons/resource/persons84137

Pfeuffer,  J
Department Physiology of Cognitive Processes, Max Planck Institute for Biological Cybernetics, Max Planck Society;

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Zitation

Zappe, A., Merkle, H., Logothetis, N., & Pfeuffer, J. (2005). Continuous arterial spin labeling (CASL) in the monkey brain at high magnetic field using a three-coil approach. Poster presented at 13th Scientific Meeting of the International Society of Magnetic Resonance in Medicine (ISMRM 2005), Miami Beach, FL, USA.


Zitierlink: http://hdl.handle.net/11858/00-001M-0000-0013-D5A3-E
Zusammenfassung
CASL experiments in the monkey brain were performed at 4.7 T and 7 T using a separate labeling coil. Increased sensitivity and SNR were achieved by a custom-made three-coil setup and high magnetic field with its increased T1. We report the development and optimization of the setup and first experiments in the monkey (macaca mulatta). Parameters for continuous labeling (label power, label duration, post label delay) were optimized to measure gray matter rCBF and fCBF changes, reporting excellent multi-slice coverage at high resolution of 0.75 – 1 mm in-plane.