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Localized 1H MR Spectroscopy in the Primary Visual Cortex (V1) of the Macaque Monkey

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http://pubman.mpdl.mpg.de/cone/persons/resource/persons83997

Juchem,  C
Department Physiology of Cognitive Processes, Max Planck Institute for Biological Cybernetics, Max Planck Society;

http://pubman.mpdl.mpg.de/cone/persons/resource/persons84063

Logothetis,  NK
Department Physiology of Cognitive Processes, Max Planck Institute for Biological Cybernetics, Max Planck Society;

http://pubman.mpdl.mpg.de/cone/persons/resource/persons84137

Pfeuffer,  J
Department Physiology of Cognitive Processes, Max Planck Institute for Biological Cybernetics, Max Planck Society;

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Citation

Juchem, C., Logothetis, N., & Pfeuffer, J. (2006). Localized 1H MR Spectroscopy in the Primary Visual Cortex (V1) of the Macaque Monkey. Poster presented at 14th Scientific Meeting of the International Society of Magnetic Resonance in Medicine (ISMRM 2006), Seattle, WA, USA.


Cite as: http://hdl.handle.net/11858/00-001M-0000-0013-D205-E
Abstract
The primary visual cortex (V1) is one of the elementary targets, when visual function and cortical reorganization are investigated. Neurotransmitters and substances involved in the energy metabolism of the brain are thought to be key compounds for a deeper understanding of the underlying processes. Here, 1H MR spectroscopy from small volumes positioned exclusively within the macaque V1 in direct vicinity to the cranial bone is reported. Optimizations in combined passive and active shimming, outer volume suppression and RF pulse design allowed the full quantification of 10 metabolites including creatine and phosphocreatine from a very localized voxel of monkey cortex V1 (5x1.6x5 mm3, 40 ìL).