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Hemodynamic Response to 0,1 ms (at 7T) and 1 ms (at 3T) Stimulus is Detectable in Human Subjects

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http://pubman.mpdl.mpg.de/cone/persons/resource/persons84323

Yesilyurt,  B
Department High-Field Magnetic Resonance, Max Planck Institute for Biological Cybernetics, Max Planck Society;

http://pubman.mpdl.mpg.de/cone/persons/resource/persons84269

Uludag,  K
Department High-Field Magnetic Resonance, Max Planck Institute for Biological Cybernetics, Max Planck Society;

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Citation

Yesilyurt, B., Ugurbil, K., & Uludag, K. (2006). Hemodynamic Response to 0,1 ms (at 7T) and 1 ms (at 3T) Stimulus is Detectable in Human Subjects. Poster presented at 12th Annual Meeting of the Organization for Human Brain Mapping (HBM 2006), Firenze, Italy.


Cite as: http://hdl.handle.net/11858/00-001M-0000-0013-D163-2
Abstract
In a previous study, we have shown that in humans it is possible to detect blood oxygenation level dependent (BOLD) signal changes evoked by a visual stimulus presented only for 5 ms. Moreover, we observed that the extrapolated intercept at 0ms stimulus duration was not zero suggesting that below a specific stimulus duration the hemodynamic response remains constant. In this study, we have expanded our previous investigation on the temporal behavior of the BOLD response by zooming into the time scale of stimulus durations as short as 0,1 to 5ms (at 7T) and 1 to 5ms (at 3T), in order to evaluate if there is indeed a minimum hemodynamic response.