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Blood Oxygenation Level Dependent (BOLD) Signal Response to Stimulus Duration of 1 ms is Measurable in Human Subjects

MPS-Authors
http://pubman.mpdl.mpg.de/cone/persons/resource/persons84323

Yesilyurt,  B
Department High-Field Magnetic Resonance, Max Planck Institute for Biological Cybernetics, Max Planck Society;

http://pubman.mpdl.mpg.de/cone/persons/resource/persons84269

Uludag,  K
Department High-Field Magnetic Resonance, Max Planck Institute for Biological Cybernetics, Max Planck Society;

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Citation

Yesilyurt, B., Ugurbil, K., & Uludag, K. (2006). Blood Oxygenation Level Dependent (BOLD) Signal Response to Stimulus Duration of 1 ms is Measurable in Human Subjects. Poster presented at 23rd Annual Scientific Meeting of the ESMRMB 2006, Warsaw, Poland.


Cite as: http://hdl.handle.net/11858/00-001M-0000-0013-D063-A
Abstract
In a previous study, we have shown that in human subjects it is possible to detect blood oxygenation level dependent (BOLD) signal changes evoked by a visual stimulus presented only for 5 ms. Moreover, we observed that at this ultrashort stimulus duration a) the response is highly non-linear compared to 50ms, 250ms and 1s stimulus b) the extrapolated intercept at 0ms stimulus duration was not zero suggesting that below a specific stimulus duration the hemodynamic response remains constant