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Insights into the dynamics of hemodynamic response to millisecond stimulus duration: A fMRI and VEP combination study

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http://pubman.mpdl.mpg.de/cone/persons/resource/persons84323

Yesilyurt,  B
Department High-Field Magnetic Resonance, Max Planck Institute for Biological Cybernetics, Max Planck Society;

http://pubman.mpdl.mpg.de/cone/persons/resource/persons84313

Whittingstall,  K
Department Physiology of Cognitive Processes, Max Planck Institute for Biological Cybernetics, Max Planck Society;

http://pubman.mpdl.mpg.de/cone/persons/resource/persons84269

Uludag,  K
Department High-Field Magnetic Resonance, Max Planck Institute for Biological Cybernetics, Max Planck Society;

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Citation

Yesilyurt, B., Whittingstall, K., Ugurbil, K., & Uludag, K. (2007). Insights into the dynamics of hemodynamic response to millisecond stimulus duration: A fMRI and VEP combination study. Poster presented at 2007 Joint Annual Meeting ISMRM-ESMRMB, Berlin, Germany.


Cite as: http://hdl.handle.net/11858/00-001M-0000-0013-CDDB-2
Abstract
In a previous study, we observed that the intercept of BOLD integral at 0ms stimulus duration was not zero. This suggests, below specific stimulus duration the hemodynamic response remains constant. In order to gain insights about the dynamics of BOLD and neural response at ultrashort stimulus durations (0.1 to 5ms), we performed a VEP and fMRI combination study. We have observed that a) a hemodynamic response to 0.1 ms stimulus duration is detectable in human subjects b) both BOLD integral and VEP amplitude increase monotonically with increasing stimulus duration and c) they show nearly similar nonlinearities.