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Single Voxel MR Spectroscopy with Echo Times Below 2 ms at 16.4 T in the Rat Brain: First in vivo Results

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http://pubman.mpdl.mpg.de/cone/persons/resource/persons83793

Balla,  DZ
Department High-Field Magnetic Resonance, Max Planck Institute for Biological Cybernetics, Max Planck Society;

http://pubman.mpdl.mpg.de/cone/persons/resource/persons83980

Hong,  S-T
Department High-Field Magnetic Resonance, Max Planck Institute for Biological Cybernetics, Max Planck Society;

http://pubman.mpdl.mpg.de/cone/persons/resource/persons84213

Shajan,  G
Department High-Field Magnetic Resonance, Max Planck Institute for Biological Cybernetics, Max Planck Society;

http://pubman.mpdl.mpg.de/cone/persons/resource/persons84145

Pohmann,  R
Department High-Field Magnetic Resonance, Max Planck Institute for Biological Cybernetics, Max Planck Society;

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Citation

Balla, D., Hong, S.-T., Shajan, G., Pohmann, R., & Ugurbil, K. (2008). Single Voxel MR Spectroscopy with Echo Times Below 2 ms at 16.4 T in the Rat Brain: First in vivo Results. Poster presented at 16th Scientific Meeting and Exhibition of the International Society of Magnetic Resonance in Medicine (ISMRM 2008), Toronto, Canada.


Cite as: http://hdl.handle.net/11858/00-001M-0000-0013-C9A1-2
Abstract
Single voxel MRS techniques employ at least three RF-pulses to generate an echo in the selected volume and gradients to dephase magnetization in the outer region. During the time between excitation and acquisition, relaxation effects and phase modulation by J-couplings affect the NMR signal. The STEAM sequence can be applied with very short echo times to obtain localized spectra containing fast decaying components and peaks from all detectable coupled resonances. We show in vivo spectra from the rat brain acquired at 16.4 T with localized spectroscopy using echo times below 2 ms and compare them to results from the literature.