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Meeting Abstract

Positive and negative BOLD-signals from blood vessels in monkey visual cortex

MPG-Autoren
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Goense,  JBM
Department Physiology of Cognitive Processes, Max Planck Institute for Biological Cybernetics, Max Planck Society;
Max Planck Institute for Biological Cybernetics, Max Planck Society;

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Logothetis,  NK
Department Physiology of Cognitive Processes, Max Planck Institute for Biological Cybernetics, Max Planck Society;
Max Planck Institute for Biological Cybernetics, Max Planck Society;

Externe Ressourcen

https://cds.ismrm.org/ismrm-2008/files/1_program.pdf
(Zusammenfassung)

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Zitation

Goense, J., & Logothetis, N. (2008). Positive and negative BOLD-signals from blood vessels in monkey visual cortex. In 16th Scientific Meeting and Exhibition of the International Society of Magnetic Resonance in Medicine (ISMRM 2008) (pp. 27).


Zitierlink: https://hdl.handle.net/11858/00-001M-0000-0013-C99F-A
Zusammenfassung
High-resolution fMRI can aid in determining to what extent the BOLD signal arises from capillaries or larger vessels. In high-resolution functional activation maps both positive and negative BOLD signals associated with vessels were observed; this was seen for both GE- and SE-BOLD. Because of its higher specificity, the SE-BOLD signal was used to investigate the origin of these vessel signals. The location of the SE-BOLD signal from veins changed when the direction of the gradients was changed. This is in contrast to the peak SE-BOLD occurring in layer IV which arises from capillaries, and was insensitive to gradient reversal.