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TurboCRAZED BOLD imaging detects specific activation in the rat brain after somatosensory stimulation at 16.4 Tesla

MPS-Authors
http://pubman.mpdl.mpg.de/cone/persons/resource/persons83793

Balla,  DZ
Department High-Field Magnetic Resonance, Max Planck Institute for Biological Cybernetics, Max Planck Society;

http://pubman.mpdl.mpg.de/cone/persons/resource/persons84317

Wiesner,  HM
Department High-Field Magnetic Resonance, Max Planck Institute for Biological Cybernetics, Max Planck Society;

http://pubman.mpdl.mpg.de/cone/persons/resource/persons84213

Shajan,  G
Department High-Field Magnetic Resonance, Max Planck Institute for Biological Cybernetics, Max Planck Society;

http://pubman.mpdl.mpg.de/cone/persons/resource/persons84145

Pohmann,  R
Department High-Field Magnetic Resonance, Max Planck Institute for Biological Cybernetics, Max Planck Society;

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Citation

Balla, D., Wiesner, H., Shajan, G., Faber, C., & Pohmann, R. (2009). TurboCRAZED BOLD imaging detects specific activation in the rat brain after somatosensory stimulation at 16.4 Tesla. Poster presented at 17th Annual Meeting of the International Society for Magnetic Resonance in Medicine (ISMRM 2009), Honolulu, HI, USA.


Cite as: http://hdl.handle.net/11858/00-001M-0000-0013-C577-4
Abstract
The TurboCRAZED sequence is based on intermolecular multiple-quantum coherence (iMQC) detection. The provided contrast is weighted by tissue structure and this weighting can be adjusted by modifying one sequence parameter. We employed TurboCRAZED for the first time for stimulation-induced BOLD fMRI in animals. Electrical forepaw stimulation activated only a region in the primary sensory cortex as expected. Technical details of the sequence and the extensive animal monitoring used during the experiments will be discussed.