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Pushing the limits: Ultrafast 2D accelerated High Resolution Whole-Head Volumetric Functional Imaging at 7 Tesla

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http://pubman.mpdl.mpg.de/cone/persons/resource/persons84107

Nguyen,  T
Department Physiology of Cognitive Processes, Max Planck Institute for Biological Cybernetics, Max Planck Society;
Department High-Field Magnetic Resonance, Max Planck Institute for Biological Cybernetics, Max Planck Society;

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Citation

Nguyen, T., Moeller S, Goerke U, Yacoub, E., & Ugurbil, K. (2009). Pushing the limits: Ultrafast 2D accelerated High Resolution Whole-Head Volumetric Functional Imaging at 7 Tesla. Poster presented at 17th Annual Meeting of the International Society for Magnetic Resonance in Medicine (ISMRM 2009), Honolulu, HI, USA.


Cite as: http://hdl.handle.net/11858/00-001M-0000-0013-C571-0
Abstract
In the tendency towards high-field imaging, three-dimensional (3D) acquisition has potential advantages over its two-dimensional counterpart for functional MRI (fMRI). However, multi-slice 2D-EPI methods remain the conventional sequence in fMRI. Although various advanced 3D schemes have alternatively been applied, they come with individual limitations and are not widely available. The 3D-EPI sequence similarly presents temporal constraints, but holds the potential to be feasible by using the increased signal- and contrast-to-noise ratio of ultrahigh magnetic fields combined with the higher parallel imaging performance feasible at ultra-high fields. A hybrid 3D-EPI then offers the possibility for high 2D acceleration. This potential is exploited in this study at 7 Tesla to overcome the limitations and compare results with 2D acquisition and 1D acceleration. Results show the feasibility of a highly accelerated hybrid 3D-EPI scheme for high resolution whole-head acquisition in high-field fMRI, presenting excellent functional results.