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Evaluation of Minimum Scan Time for High Quality Quantitative in vivo 1H MR Spectroscopy at 16.4T

MPS-Authors
http://pubman.mpdl.mpg.de/cone/persons/resource/persons83980

Hong,  S-T
Department High-Field Magnetic Resonance, Max Planck Institute for Biological Cybernetics, Max Planck Society;

http://pubman.mpdl.mpg.de/cone/persons/resource/persons83793

Balla,  DZ
Department High-Field Magnetic Resonance, Max Planck Institute for Biological Cybernetics, Max Planck Society;

http://pubman.mpdl.mpg.de/cone/persons/resource/persons84145

Pohmann,  R
Department High-Field Magnetic Resonance, Max Planck Institute for Biological Cybernetics, Max Planck Society;

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Citation

Hong, S.-T., Balla, D., Choi, C., & Pohmann, R. (2010). Evaluation of Minimum Scan Time for High Quality Quantitative in vivo 1H MR Spectroscopy at 16.4T. Poster presented at ISMRM-ESMRMB Joint Annual Meeting 2010, Stockholm, Sweden.


Cite as: http://hdl.handle.net/11858/00-001M-0000-0013-C072-7
Abstract
Localized in vivo 1H NMR spectroscopy requires significantly high number of averages compared to other MR imaging techniques. Precise analysis on spectra obtained at 16.4T was performed to determine the minimal number of averages, necessary for quantifying nineteen metabolites with average CRLBs of below 20. The results demonstrated that 64 averages were sufficient to quantify most metabolites reliably except weakly represented metabolites such as alanine, glycine and phosphorylcholine.