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Human imaging at 9.4 T using T2*-, phase-, and susceptibility-weighted contrast

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http://pubman.mpdl.mpg.de/cone/persons/resource/persons83838

Budde,  J
Department High-Field Magnetic Resonance, Max Planck Institute for Biological Cybernetics, Max Planck Society;

http://pubman.mpdl.mpg.de/cone/persons/resource/persons84213

Shajan,  G
Department High-Field Magnetic Resonance, Max Planck Institute for Biological Cybernetics, Max Planck Society;

http://pubman.mpdl.mpg.de/cone/persons/resource/persons83973

Hoffmann,  J
Department High-Field Magnetic Resonance, Max Planck Institute for Biological Cybernetics, Max Planck Society;

http://pubman.mpdl.mpg.de/cone/persons/resource/persons84145

Pohmann,  R
Department High-Field Magnetic Resonance, Max Planck Institute for Biological Cybernetics, Max Planck Society;

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Citation

Budde, J., Shajan, G., Hoffmann, J., Ugurbil, K., & Pohmann, R. (2011). Human imaging at 9.4 T using T2*-, phase-, and susceptibility-weighted contrast. Magnetic Resonance in Medicine, 65(2), 544-550. doi:10.1002/mrm.22632.


Cite as: http://hdl.handle.net/11858/00-001M-0000-0013-BC8C-C
Abstract
The effect of susceptibility differences on an MR image is known to increase with field strength. Magnetic field inhomogeneities within the voxels influence the apparent transverse relaxation time T2*, while effects due to different precession frequencies between voxels caused by local field variations are evident in the image phase, and susceptibility-weighted imaging highlights the veins and deep brain structures. Here, these three contrast mechanisms are examined at a field strength of 9.4 T. The T2* maps generated allow the identification of white matter structures not visible in conventional images. Phase images with in-plane resolutions down to 130 amp;amp;956;m were obtained, showing high gray/white matter contrast and allowing the identification of internal cortical structures. The susceptibility-weighted images yield excellent visibility of small venous structures and attain an in-plane resolution of 175 mikro-m.