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Non-water suppressed proton MR spectroscopy allows spectral quality improvement in the human cervical spinal cord

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http://pubman.mpdl.mpg.de/cone/persons/resource/persons84402

Henning,  A
Department High-Field Magnetic Resonance, Max Planck Institute for Biological Cybernetics, Max Planck Society;

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Citation

Hock, A., MacMillan E, Fuchs A, Kreis R, Boesiger P, Kollias, S., & Henning, A. (2011). Non-water suppressed proton MR spectroscopy allows spectral quality improvement in the human cervical spinal cord. Talk presented at 19th Annual Meeting and Exhibition of the International Society for Magnetic Resonance in Medicine (ISMRM 2011). Montréal, Canada.


Cite as: http://hdl.handle.net/11858/00-001M-0000-0013-BC1C-8
Abstract
1H non-water-suppressed MR spectroscopy with the metabolite cycling technique is introduced for measurements in the spinal cord. The high SNR of the water peak allows frequency alignment of FIDs before signal averaging to improve the spectral quality (line shape and SNR) of the metabolite peaks. A study on 3 volunteers demonstrates the feasibility of the method and results in a higher SNR for metabolite cycled spectra as compared with VAPOR water suppressed acquisitions: (mean ± SD) 6.3 ± 0.6, and 4.7 ± 0.6, respectively.