de.mpg.escidoc.pubman.appbase.FacesBean
Deutsch
 
Hilfe Wegweiser Impressum Kontakt Einloggen
  DetailsucheBrowse

Datensatz

DATENSATZ AKTIONENEXPORT

Freigegeben

Vortrag

In vivo visualization of pancreatic islets in the mouse

MPG-Autoren
http://pubman.mpdl.mpg.de/cone/persons/resource/persons83793

Balla,  D
Department High-Field Magnetic Resonance, Max Planck Institute for Biological Cybernetics, Max Planck Society;

http://pubman.mpdl.mpg.de/cone/persons/resource/persons83941

Gottschalk,  S
Department High-Field Magnetic Resonance, Max Planck Institute for Biological Cybernetics, Max Planck Society;

http://pubman.mpdl.mpg.de/cone/persons/resource/persons84213

Shajan,  G
Department High-Field Magnetic Resonance, Max Planck Institute for Biological Cybernetics, Max Planck Society;

http://pubman.mpdl.mpg.de/cone/persons/resource/persons84145

Ueberberg S, Schneider S, Pohmann,  R
Department High-Field Magnetic Resonance, Max Planck Institute for Biological Cybernetics, Max Planck Society;

http://pubman.mpdl.mpg.de/cone/persons/resource/persons83903

Engelmann,  J
Department High-Field Magnetic Resonance, Max Planck Institute for Biological Cybernetics, Max Planck Society;

Externe Ressourcen
Es sind keine Externen Ressourcen verfügbar
Volltexte (frei zugänglich)
Es sind keine frei zugänglichen Volltexte verfügbar
Ergänzendes Material (frei zugänglich)
Es sind keine frei zugänglichen Ergänzenden Materialien verfügbar
Zitation

Balla, D., Gottschalk, S., Shajan, G., Ueberberg S, Schneider S, Pohmann, R., & Engelmann, J. (2011). In vivo visualization of pancreatic islets in the mouse. Talk presented at 19th Annual Meeting and Exhibition of the International Society for Magnetic Resonance in Medicine (ISMRM 2011). Montréal, Canada.


Zitierlink: http://hdl.handle.net/11858/00-001M-0000-0013-BC18-0
Zusammenfassung
Detection of single pancreatic islets has many applications in diabetes research, but can be achieved in vivo with proton MRI only after transplantation of ex vivo labeled islets. Recently, successful visualization of islets in the excised mouse pancreas at 16.4T following i.v. injection of a novel beta-cell specific paramagnetic contrast agent was reported. Here we present the methodical optimization for in vivo experiments. Signal efficient 2D acquisition methods were considered. Best results were obtained with a two slice navigator based sequence. Single islets are visualized for the first time in vivo in mice after i.v. administration of a labeling agent.