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New Technique for Metabolite Cycled Non-Water-Suppressed Proton Spectroscopy in the Human Brain at 7T

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http://pubman.mpdl.mpg.de/cone/persons/resource/persons84402

Henning,  A
Department High-Field Magnetic Resonance, Max Planck Institute for Biological Cybernetics, Max Planck Society;

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Citation

MacMillan, E., Kreis R, Fuchs A, Versluis MJ, Boesch C, Boesiger, P., & Henning, A. (2011). New Technique for Metabolite Cycled Non-Water-Suppressed Proton Spectroscopy in the Human Brain at 7T. Poster presented at 19th Annual Meeting and Exhibition of the International Society for Magnetic Resonance in Medicine (ISMRM 2011), Montréal, Canada.


Cite as: http://hdl.handle.net/11858/00-001M-0000-0013-BC06-5
Abstract
Non-water-suppressed MRS via metabolite cycling in the mixing period of STEAM was introduced to benefit from the ability to perform corrections on individual FIDs to increase SNR, and to provide a new tool to investigate exchangeable protons. At 7T, this technique successfully reduced the gradient sideband artifacts and water baseline tail to well below the prominent upfield peaks, and showed the same information as VAPOR water-suppressed spectroscopy. Furthermore, the 7.9ppm NAA peak was much better resolved with metabolite cycled non-water-suppressed MRS at 7T when compared to previous work at 3T.