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Human fMRI at 9.4 T: Preliminary Results

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http://pubman.mpdl.mpg.de/cone/persons/resource/persons83838

Budde,  J
Department High-Field Magnetic Resonance, Max Planck Institute for Biological Cybernetics, Max Planck Society;

http://pubman.mpdl.mpg.de/cone/persons/resource/persons84092

Mühlbauer,  F
Department High-Field Magnetic Resonance, Max Planck Institute for Biological Cybernetics, Max Planck Society;

http://pubman.mpdl.mpg.de/cone/persons/resource/persons84213

Shajan,  G
Department High-Field Magnetic Resonance, Max Planck Institute for Biological Cybernetics, Max Planck Society;

http://pubman.mpdl.mpg.de/cone/persons/resource/persons84145

Pohmann,  R
Department High-Field Magnetic Resonance, Max Planck Institute for Biological Cybernetics, Max Planck Society;

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Citation

Budde, J., Mühlbauer, F., Shajan, G., Zaitsev, M., & Pohmann, R. (2011). Human fMRI at 9.4 T: Preliminary Results. Poster presented at 19th Annual Meeting and Exhibition of the International Society for Magnetic Resonance in Medicine (ISMRM 2011), Montréal, Canada.


Cite as: http://hdl.handle.net/11858/00-001M-0000-0013-BC02-D
Abstract
With increasing field, the MR signal-to-noise ratio is expected to grow linearly, while a BOLD increase of more than linear is expected [1]. In addition, a higher emphasis on signal from microvasculature is predicted, especially for SE-EPI [2,3], while GE - EPI remains more specific to the macrovasculature. Here, a field strength of 9.4 T is used for the first time to measure BOLD activation during finger tapping of a human subject. To examine the signal contributions of tissue and veins, the functional maps were overlaid on T2*-weighted GRE images revealing venous vasculature at high detail. Co-registration of both image modalities demonstrates where the functional signal coincides with venous structures.