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Functional Quantitative Susceptibility Mapping (fQSM)

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http://pubman.mpdl.mpg.de/cone/persons/resource/persons83793

Balla,  DZ
Department High-Field Magnetic Resonance, Max Planck Institute for Biological Cybernetics, Max Planck Society;

http://pubman.mpdl.mpg.de/cone/persons/resource/persons84187

Sanchez-Panchuelo RM, Wharton S, Hagberg GE, Scheffler,  K
Department High-Field Magnetic Resonance, Max Planck Institute for Biological Cybernetics, Max Planck Society;

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Balla, D., Sanchez-Panchuelo RM, Wharton S, Hagberg GE, Scheffler, K., Francis, S., & Bowtell, R. (2012). Functional Quantitative Susceptibility Mapping (fQSM). Talk presented at 20th Annual Meeting and Exhibition of the International Society for Magnetic Resonance in Medicine (ISMRM 2012). Melbourne, Australia.


Cite as: http://hdl.handle.net/11858/00-001M-0000-0013-B7C4-7
Abstract
Quantitative susceptibility mapping (QSM) was performed on fMRI time-series to reconstruct maps with activation induced local susceptibility changes. A multi-step image processing algorithm was developed for filtering out unwanted temporal and spatial signal variations. The method was validated on GE-EPI BOLD-fMRI datasets acquired at 7T with 1mm isotropic resolution during the application of visual, motor and somatosensory activation paradigms. Series of high-quality phase and susceptibility maps with minimal temporal noise were reconstructed, which resulted in activation maps corresponding to estimations from the modulus data. Functional QSM (fQSM) allows for quantification of the BOLD-effect for any time-series with phase information.